In the war between heaven and hell the angels have lost. The demon army is poised to destroy the world and burn it to ash one city at a time. Sam, possessed by Lucifer at the head of the army. All seems lost, but a message arrives for the last remaining angels and human resistance. Sam is offering them a deal, he will not destroy the earth or march on heaven, his demons will remain in hell or only possess the dead or dying on earth, and there will be no war for a thousand years. The catch? The angels must hand over their "savior", Dean.
Believing this will give them time to muster their forces and come up with a way to defeat Sam, the angels agree almost unanimously to give Dean to Sam. Even Dean agrees to do it, hoping he can somehow reach his brother and lover and save him. Castiel however refuses to let them hand over Dean to Sam to face death or worse, he takes Dean and runs. However with both the armies of heaven and hell after them, where can they possibly run?
This idea would involve some Dean/Castiel, Dean/Sam, and possibly Dean/Sam/Castiel